Japanese plum extract may suppress dangerous stomach bacteria

A study conducted by Chinese scientists indicates that an extract from the Japanese plum, also known as "mume," possesses anti-bacterial properties against Helicobacter pylori. This bacterium is responsible for serious gastric issues.

Screening of edible plant extracts

The research team analyzed extracts from 17 types of edible plants and fruits to identify natural compounds capable of suppressing Helicobacter pylori. The Japanese plum emerged as the most effective candidate among those tested.

According to the findings, the fruit's extract inhibits bacterial growth, including strains resistant to multiple antibiotics. Additionally, it reduces the activity of genes that enable the bacteria to damage stomach cells.

Effects on inflammation and tissue repair

In experiments involving mice, the extract decreased inflammation and promoted the restoration of the gastric mucosa. Tests performed on human cells further confirmed its protective characteristics.

Scientists discovered that organic acids present in the fruit likely play a significant role. These compounds interact with the CagA protein, which assists the bacteria in damaging cells and is linked to an increased risk of stomach cancer.

Limitations of current laboratory evidence

The study authors noted that their results are based on experiments using laboratory mice and human cells. Consequently, the data does not definitively prove that consuming this fruit can eliminate infection in humans.

However, the researchers stated that the findings offer promising prospects for utilizing the Japanese plum to develop treatments for Helicobacter pylori.