Horse Milk Shows Protective Effect Against Ulcerative Colitis in New Study

A recent study published in the journal *Food & Function* indicates that horse milk may protect the intestines from ulcerative colitis—a chronic inflammatory disease associated with increased risk of colorectal cancer.

How horse milk and its extracellular vesicles reduced disease severity

In laboratory experiments conducted on mice, researchers examined the effects of horse milk and the extracellular vesicles it contains. These microscopic particles mediate intercellular transport of biologically active substances. Results demonstrated that both horse milk and its extracellular vesicles markedly alleviated disease symptoms. The observed effects included reduced intestinal inflammation, repair of the intestinal mucosal lining, decreased levels of pro-inflammatory molecules, and improved overall health status in the animals.

Microbiota modulation by milk and vesicles

Horse milk contributed to restoring balance in gut microbial composition. Specifically, it increased the abundance of beneficial bacteria linked to dietary fiber digestion. In parallel, the extracellular vesicles enhanced the growth of microorganisms producing butyric acid—a compound known to play a key role in intestinal protection and inflammation reduction.

Multitarget mechanisms of action

According to the researchers, horse milk exerts its effect through multiple simultaneous biological pathways: regulation of immune response, restoration of gut bacterial equilibrium, and improvement of metabolic function. These combined actions position horse milk as a promising candidate for supporting future therapies targeting inflammatory bowel diseases.

Nutritional profile and additional applications

Multiple studies cited in the report note that horse milk is rich in minerals and vitamins that support immune function and reduce systemic inflammation. It also offers digestive benefits and has been used, in some cases, as adjunctive support in treating certain skin conditions—including eczema and psoriasis.

The findings were reported by Lenta.ru.